The Macedonian Empire was established (333 BC)

Darius III was defeated by Alexander the Great. 
370 The monk Buddhagosa (ca. 370–450) compiled and edited once for all the Pali-Canon in Sri Lanka. 
The inner development of the Theravada is finalized in certain ways. Shakuntalam and Kamasutra were written during this period, Aryabhatta (476 – 550) achieved feats in Astronomy and the Hindu Bhakti yoga movement emerged.